Improved incidence estimates from linked vs. stand-alone electronic health records
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Published version
Author(s)
Millett, ER
Quint, JK
De Stavola, BL
Smeeth, L
Thomas, SL
Type
Journal Article
Abstract
OBJECTIVE: Electronic health records are widely used for public health research, and linked data sources are increasingly available. The added value of using linked records over stand-alone data has not been quantified for common conditions such as community-acquired pneumonia (CAP). STUDY DESIGN AND SETTING: Our cohort comprised English patients aged ≥65 years from the Clinical Practice Research Datalink, eligible for record linkage to Hospital Episode Statistics. Stand-alone general practice (GP) records were used to calculate CAP incidence over time using population-averaged Poisson regression. Incidence was then recalculated for the same patients using their linked GP-hospital admission data. Results of the two analyses were compared. RESULTS: Over 900,000 patients were included in each analysis. Population-averaged CAP incidence was 39% higher using the linked data than stand-alone data. This difference grew over time from 7% in 1997 to 83% by 2010. An increasingly larger number of pneumonia events were recorded in the hospital admission data compared to the GP data over time. CONCLUSION: Use of primary or secondary care data in isolation may not give accurate incidence estimates for important infections in older populations. Further work is needed to establish the extent of this finding in other diseases, age groups, and populations.
Date Issued
2016-01-09
Date Acceptance
2016-01-04
Citation
Journal of Clinical Epidemiology, 2016, 75, pp.66-69
ISSN
1878-5921
Publisher
Elsevier
Start Page
66
End Page
69
Journal / Book Title
Journal of Clinical Epidemiology
Volume
75
Copyright Statement
© 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/
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License URL
Identifier
PII: S0895-4356(16)00013-5
Subjects
Aged
Cohort
Data linkage
Electronic health records
England/epidemiology
Pneumonia
Publication Status
Published