Human Milk and Allergic Diseases: An Unsolved Puzzle

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Human Milk and Allergic Diseases: An Unsolved Puzzle.pdf (721.43 KB)

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Author(s)

Munblit, D

Peroni, DG

Boix-Amoros, A

Hsu, PS

Van't Land, B

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Type

Journal Article

Abstract

There is conflicting evidence on the protective role of breastfeeding in relation to the development of allergic sensitisation and allergic disease. Studies vary in methodology and definition of outcomes, which lead to considerable heterogeneity. Human milk composition varies both within and between individuals, which may partially explain conflicting data. It is known that human milk composition is very complex and contains variable levels of immune active molecules, oligosaccharides, metabolites, vitamins and other nutrients and microbial content. Existing evidence suggests that modulation of human breast milk composition has potential for preventing allergic diseases in early life. In this review, we discuss associations between breastfeeding/human milk composition and allergy development.

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Date Issued

2017-08-17

Date Acceptance

2017-08-01

Citation

NUTRIENTS, 2017, 9 (8)

URI

http://hdl.handle.net/10044/1/52592

DOI

https://www.dx.doi.org/10.3390/nu9080894

ISSN

2072-6643

Publisher

MDPI AG

Journal / Book Title

NUTRIENTS

Volume

9

Issue

8

Copyright Statement

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access
article distributed under the terms and conditions of the Creative Commons Attribution
(CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000408688100101&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Subjects

Science & Technology

Life Sciences & Biomedicine

Nutrition & Dietetics

breastfeeding

human milk

allergy

allergic diseases

oligosaccharides

microbiome

cytokines

thymus

BREAST-FED INFANTS

GROWTH-FACTOR-BETA

POLYUNSATURATED FATTY-ACIDS

PROSPECTIVE BIRTH COHORT

VITAMIN-D STATUS

PATTERN-RECOGNITION RECEPTOR

RANDOMIZED CONTROLLED-TRIAL

SECRETORY IMMUNOGLOBULIN-A

UNMETABOLIZED FOLIC-ACID

FORMULA-FED INFANTS

1111 Nutrition And Dietetics

Publication Status

Published

Article Number

ARTN 894