Polyunsaturated lipids kill senescent cells by ferroptosis
File(s) Spotlight cell metabolismForSpiral.pdf (236.79 KB)
Accepted version
Author(s)
D’Ambrosio, M
Gil, J
Type
Journal Article
Abstract
In a recent issue of Cell Press Blue, Zhang et al. identify two polyunsaturated lipids that selectively eliminate senescent cells by inducing ferroptosis, uncovering this iron-dependent cell death pathway as a new vulnerability for senescent cells. Their findings position ferroptosis induction as a promising strategy for targeting senescence and ageing-associated diseases.
Date Issued
2026-04-07
Date Acceptance
2026-02-27
Citation
Cell Metabolism, 2026, 38 (4), pp.643-644
ISSN
1550-4131
Publisher
Cell Press
Start Page
643
End Page
644
Journal / Book Title
Cell Metabolism
Volume
38
Issue
4
Copyright Statement
Copyright © 2026 Elsevier Inc. This is the author’s accepted manuscript made available under a CC-BY licence in accordance with Imperial’s Research Publications Open Access policy (www.imperial.ac.uk/oa-policy)
License URL
Publication Status
Published
Date Publish Online
2026-04-07
