Baseline mental health status and early psychiatric outcomes after metabolic-bariatric surgery: a retrospective cohort study
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Accepted version
Author(s)
Type
Journal Article
Abstract
Objective: To evaluate whether documented preoperative mental health (MH) conditions were associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery (MBS).
Methods: A retrospective cohort study of adults who underwent primary MBS at a tertiary UK bariatric centre between April 2021 and March 2024 was conducted. Preoperative MH conditions and postoperative outcomes were identified via review of electronic health records. Comparisons between groups were analysed using Fisher’s exact test and regression models adjusted for age, sex, preoperative BMI, and surgery type.
Results: Among 482 patients, 217 (45.0%) had at least one documented preoperative MH condition. During 2-year follow-up, suicidal ideation was recorded in 6/217 (2.8%) in the MH group versus 1/265 (0.4%) in the non-MH group and self-harm (including suicide attempt) in 5/217 (2.3%) versus 1/265 (0.4%), respectively. Preoperative MH conditions were associated with higher odds of postoperative suicidal ideation (OR 6.75, 95% CI 1.09–41.86; p=0.0420), while the association with self-harm was directionally similar but not statistically significant (OR 5.10, 95% CI 0.80–32.72; p=0.0860). Weight-loss and metabolic outcomes did not differ materially by baseline MH status.
Conclusions: In this single-centre cohort, patients with documented preoperative MH conditions achieved comparable metabolic benefit after surgery but had higher recorded early suicidality-related events. Although causality cannot be inferred, these findings support structured postoperative MH follow-up.
Key Points
· Preoperative mental health (MH) conditions were documented in 45.0% of patients.
· At 2 years, suicidal ideation occurred in 2.8% with MH conditions and 0.4% without.
· Adjusted odds of suicidal ideation were 6.75x higher in people with MH conditions.
· Two-year weight-loss and metabolic outcomes were similar between groups.
Methods: A retrospective cohort study of adults who underwent primary MBS at a tertiary UK bariatric centre between April 2021 and March 2024 was conducted. Preoperative MH conditions and postoperative outcomes were identified via review of electronic health records. Comparisons between groups were analysed using Fisher’s exact test and regression models adjusted for age, sex, preoperative BMI, and surgery type.
Results: Among 482 patients, 217 (45.0%) had at least one documented preoperative MH condition. During 2-year follow-up, suicidal ideation was recorded in 6/217 (2.8%) in the MH group versus 1/265 (0.4%) in the non-MH group and self-harm (including suicide attempt) in 5/217 (2.3%) versus 1/265 (0.4%), respectively. Preoperative MH conditions were associated with higher odds of postoperative suicidal ideation (OR 6.75, 95% CI 1.09–41.86; p=0.0420), while the association with self-harm was directionally similar but not statistically significant (OR 5.10, 95% CI 0.80–32.72; p=0.0860). Weight-loss and metabolic outcomes did not differ materially by baseline MH status.
Conclusions: In this single-centre cohort, patients with documented preoperative MH conditions achieved comparable metabolic benefit after surgery but had higher recorded early suicidality-related events. Although causality cannot be inferred, these findings support structured postoperative MH follow-up.
Key Points
· Preoperative mental health (MH) conditions were documented in 45.0% of patients.
· At 2 years, suicidal ideation occurred in 2.8% with MH conditions and 0.4% without.
· Adjusted odds of suicidal ideation were 6.75x higher in people with MH conditions.
· Two-year weight-loss and metabolic outcomes were similar between groups.
Date Acceptance
2026-08-25
Citation
Obesity Surgery
ISSN
0960-8923
Publisher
Springer
Journal / Book Title
Obesity Surgery
Copyright Statement
Copyright This paper is embargoed until publication. Once published the Version of Record (VoR) will be available on immediate open access.
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Publication Status
Accepted