Towards a micropositioning system for targeted drug delivery in wireless capsule endoscopy
File(s)2011_EMBC_DrugDelivery_Camera.pdf (973.59 KB)
Accepted version
Author(s)
Woods, SP
Constandinou, TG
Type
Conference Paper
Abstract
This paper describes a novel micropositioning
mechanism for achieving 1ml of targeted drug delivery within wireless capsule endoscopes. The mechanism allows a needle to be positioned within a 22.5° segment of a cylindrical capsule and be extendible by up to 4mm. The mechanism achieves both these functions using only a single micromotor and occupying a volume of just 200mm³ (including micromotor), this represents only 6.6% of the total available space. Through a detailed stress analysis it has been shown that the proposed mechanism
can be fabricated using FDA approved materials and requires a power budget of under 3.3% of the available capacity. It is envisaged this mechanism would empower a new breed of capsule microrobots for therapy in addition to diagnostics for pathologies such as ulcerative colitis and small intestinal Crohn’s disease.
mechanism for achieving 1ml of targeted drug delivery within wireless capsule endoscopes. The mechanism allows a needle to be positioned within a 22.5° segment of a cylindrical capsule and be extendible by up to 4mm. The mechanism achieves both these functions using only a single micromotor and occupying a volume of just 200mm³ (including micromotor), this represents only 6.6% of the total available space. Through a detailed stress analysis it has been shown that the proposed mechanism
can be fabricated using FDA approved materials and requires a power budget of under 3.3% of the available capacity. It is envisaged this mechanism would empower a new breed of capsule microrobots for therapy in addition to diagnostics for pathologies such as ulcerative colitis and small intestinal Crohn’s disease.
Version
Accepted version
Date Issued
2011-12-01
Citation
2011, pp.7372-7375
ISBN
978-1-4244-4121-1
ISSN
1557-170X
Publisher
IEEE
Source Title
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS)
Start Page
7372
End Page
7375
Copyright Statement
© 2011 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Source
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS)
Source Place
Boston, MA, USA
Publication Status
Published
Start Date
2011-08-30
Finish Date
2011-09-03
Coverage Spatial
Boston, MA, USA