Multiple upper aerodigestive tract masses presenting with stridor – a rare case of aggressive multifocal extramedullary plasmacytoma
File(s)
Published version
Author(s)
Bujoreanu, Iulia
Hogan, Chris
Virk, Jagdeep
Type
Journal Article
Abstract
Extramedullary plasmacytomas represent a rare group of B-cell malignancies that arise outside the bone marrow and their disease process is still poorly understood. Here, we will describe a case of a 76-year-old patient who presented with a large chest wall and subglottic mass causing airway compromise and stridor. Biopsies showed atypical plasma cells with prominent nucleoli which were in keeping with an extramedullary plasmacytoma. Disease progressed despite surgical debulking, targeted radiotherapy, and multiple chemotherapy regimens. Although response to treatment is classically good, patients occasionally present with aggressive disease.
Date Issued
2022-03-01
Date Acceptance
2020-07-23
Citation
Ear, Nose and Throat Journal, 2022, 101 (3), pp.186-188
ISSN
0014-5491
Publisher
Sage
Start Page
186
End Page
188
Journal / Book Title
Ear, Nose and Throat Journal
Volume
101
Issue
3
Copyright Statement
Creative Commons CC BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE
and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE
and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
License URL
Subjects
1103 Clinical Sciences
Otorhinolaryngology
Publication Status
Published
Date Publish Online
2020-08-14