Within the context of scientific research, patient and public involvement (PPI) is defined as research performed ‘with’ or ‘by’
patients and members of the public, rather than ‘to’, ‘about’ or ‘for’ them. When carried out systematically and thoughtfully, PPI
has the potential to strengthen the quality and impact of research by fostering accountability, transparency, and relevance. There
exist numerous guidelines, frameworks and tools for supporting PPI, however, these do not account for the unique challenges faced
in psychedelic research. This paper describes the co-design of guidance intended to help build, evaluate and improve PPI in
psychedelic research. A steering group was formed to design and run a co-design workshop alongside public collaborators. Insights
from this workshop were analysed and refined into a comprehensive and readily usable guide for planning PPI specific to the field
of psychedelic research. Core values emerging from the process focused on the essential importance of trust, learning, purpose
and inclusivity. It is hoped that this guidance will be a starting point for incorporating PPI in future psychedelic research, so that it
can grow and adapt as this burgeoning field of research progresses.