The Synthetic Genome Summer Course
File(s)
Published version
OA Location
Author(s)
Blount, Ben
Ellis, Thomas
Type
Journal Article
Abstract
The Synthetic Genome Summer Course was convened with the aim of teaching a wide range of researchers the theory and practical skills behind recent advances in synthetic biology and synthetic genome science, with a focus on Sc2.0, the synthetic yeast genome project. Through software workshops, tutorials and research talks from leading members of the field, the 30 attendees learnt about relevant principles and techniques that they were then able to implement first-hand in laboratory-based practical sessions. Participants SCRaMbLEd semi-synthetic yeast strains to diversify heterologous pathways, used automation to build combinatorial pathway libraries and used CRISPR to debug fitness defects caused by synthetic chromosome design changes. Societal implications of synthetic chromosomes were explored and industrial stakeholders discussed synthetic biology from a commercial standpoint. Over the 5 days, participants gained valuable insight and acquired skills to aid them in future synthetic genome research.
Date Issued
2019-01-01
Date Acceptance
2018-11-24
Citation
Synthetic Biology, 2019, 3 (1)
ISSN
2397-7000
Publisher
Oxford University Press (OUP)
Journal / Book Title
Synthetic Biology
Volume
3
Issue
1
Copyright Statement
© The Author(s) 2018. Published by Oxford University Press.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/),which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor
Biotechnology and Biological Sciences Research Council (BBSRC)
Biotechnology and Biological Sciences Research Council (BBSRC)
Grant Number
BB/K006290/1
BB/K019791/1
Publication Status
Published
Date Publish Online
2018-11-27