Epidemiology and outcome of paediatric out-of-hospital cardiac arrests: A paediatric sub-study of the Pan-Asian resuscitation outcomes study (PAROS)
File(s)Paediatric OHCA (PAROS) manuscript (final).pdf (638.08 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
Background: The Pan Asian Resuscitation Outcomes Study (PAROS) is a retrospective study of out- of-hospital cardiac arrest(OHCA), collaborating with EMS agencies and academic centers in Japan, South Korea, Malaysia, Singapore, Taiwan, Thailand and UAE-Dubai. The objectives of this study is to describe the characteristics and outcomes, and to find factors associated with survival after paediatric OHCA. Methods: We studied all children less than 17 years of age with OHCA conveyed by EMS and non-EMS transports from January 2009 to December 2012. We did univariate and multivariate logistic regression analyses to assess the factors associated with survival-to-discharge outcomes. Results: A total of 974 children with OHCA were included. Bystander cardiopulmonary resuscitation rates ranged from 53.5% (Korea), 35.6% (Singapore) to 11.8% (UAE). Overall, 8.6% (range 0%–9.7%) of the children survived to discharge from hospital. Adolescents (13–17 years) had the highest survival rate of 13.8%. 3.7% of the children survived with good neurological outcomes of CPC 1 or 2. The independent pre-hospital factors associated with survival to discharge were witnessed arrest and initial shockable rhythm. In the sub-group analysis, pre-hospital advanced airway [odds ratio (OR) = 3.35, 95% confidence interval (CI) = 1.23–9.13] was positively associated with survival-to-discharge outcomes in children less than 13 years-old. Among adolescents, bystander CPR (OR = 2.74, 95%CI = 1.03–7.3) and initial shockable rhythm (OR = 20.51, 95%CI = 2.15–195.7) were positive factors. Conclusion: The wide variation in the survival outcomes amongst the seven countries in our study may be due to the differences in the delivery of pre-hospital interventions and bystander CPR rates.
Date Issued
2018-04-01
Date Acceptance
2018-01-26
Citation
Resuscitation, 2018, 125, pp.111-117
ISSN
0300-9572
Publisher
Elsevier
Start Page
111
End Page
117
Journal / Book Title
Resuscitation
Volume
125
Copyright Statement
© 2018 Elsevier B.V. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
Subjects
Science & Technology
Life Sciences & Biomedicine
Critical Care Medicine
Emergency Medicine
General & Internal Medicine
Paediatric paediatric
Out-of-hospital cardiac arrest
Resuscitation
Pre-hospital
Emergency medical service
Epidemiology
Outcome
Pan asian resuscitation outcome study
SURVIVAL
COUNTRIES
CHILDREN
Emergency medical service
Epidemiology
Out-of-hospital cardiac arrest
Outcome
Paediatric
Pan asian resuscitation outcome study
Pre-hospital
Resuscitation
paediatric
Adolescent
Asia
Cardiopulmonary Resuscitation
Child
Child, Preschool
Emergency Medical Services
Female
Humans
Infant
Infant, Newborn
Male
Out-of-Hospital Cardiac Arrest
Outcome Assessment (Health Care)
Population Surveillance
Prospective Studies
Humans
Cardiopulmonary Resuscitation
Population Surveillance
Prospective Studies
Adolescent
Child
Child, Preschool
Infant
Infant, Newborn
Emergency Medical Services
Outcome Assessment (Health Care)
Asia
Female
Male
Out-of-Hospital Cardiac Arrest
1103 Clinical Sciences
1117 Public Health and Health Services
Emergency & Critical Care Medicine
Publication Status
Published
Date Publish Online
2018-02-05