The biochemical systems inside a living cell are able to reliably perform complex tasks while subjected to various sources of noise. In this study we consider stochastic models of biochemical networks evolving in the presence of dynamic random environments. These environments are themselves modeled as chemical reaction networks so that the full system can be viewed as a multiscale chemical reaction network. The multiscale structure arises from the fact that the environment and the internal system may operate on different timescales. While previous results in chemical reaction network theory have established that certain dynamic behavior can be ruled out when a topological parameter, known as the network deficiency, is zero, these results fail to capture the behavior that can be observed in multiscale networks. We demonstrate that the deficiency of the network has implications for how robust it is to environmental noise. We then show how our results can be used to prove that correlations in a population of chemical reaction networks in a random environment vanish given certain topological constraints.