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  5. Risk-based antihypertensive treatment allocation in Peru: comparison of local and international guidelines analysing national health surveys between 2015-2020
 
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Risk-based antihypertensive treatment allocation in Peru: comparison of local and international guidelines analysing national health surveys between 2015-2020
File(s)
PIIS2667193X21000144.pdf (1.12 MB)
Published version
Author(s)
Carrillo-Larco, Rodrigo M
Guzman-Vilca, Wilmer Cristobal
Bernabe-Ortiz, Antonio
Type
Journal Article
Abstract
Background: While there is a growing interest in antihypertensive medication rates among people with hypertension in low- and middle-income countries, little has been described about antihypertensive medication rates among eligible people based on the absolute cardiovascular risk approach. Following the risk-based approach, we described the proportion of eligible people receiving antihypertensive medication in Peru. Methods: Analysis of six (2015-2020) national health surveys. Absolute cardiovascular risk was computed with the 2019 WHO cardiovascular risk charts and based on local guidelines. Antihypertensive treatment allocation based on the absolute cardiovascular risk was defined using the Package of essential noncommunicable (PEN) disease interventions for primary health care in low-resource settings and the HEARTS guidelines by the WHO; we also followed the recommendations by local guidelines. Results: There were 120,059 people. Overall, according to the local guidelines the 17.9% of the population would be eligible for antihypertensive medication while this estimate was 8.1% based on the WHO guidelines. At the national level, depending on the guidelines, we observed a steady trend of eligible people receiving antihypertension medication (e.g., men, local guidelines), a decreasing trend (e.g., men, <60, local guidelines) or an increasing trend (e.g., men, ≥60, local guidelines). At the sub-national level, seventeen regions showed an increasing antihypertensive treatment rate based on the local guidelines; when based on the WHO guidelines, eleven regions showed a decreasing rate. Conclusions: Peru needs to define a tool for surveillance of absolute cardiovascular risk and to monitor antihypertensive treatment allocation among high-risk people. Funding: Wellcome Trust (214185/Z/18/Z).
Date Issued
2021-09-01
Date Acceptance
2021-06-30
Citation
The Lancet Regional Health - Americas, 2021, 1
URI
http://hdl.handle.net/10044/1/91774
DOI
https://www.dx.doi.org/10.1016/j.lana.2021.100022
ISSN
2667-193X
Publisher
Elsevier
Journal / Book Title
The Lancet Regional Health - Americas
Volume
1
Copyright Statement
© 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC-BY license (http://creativecommons.org/licenses/by/4.0/)
License URL
http://creativecommons.org/licenses/by/4.0/
Sponsor
Wellcome Trust
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/34541568
PII: S2667-193X(21)00014-4
Grant Number
214185/Z/18/Z
Subjects
cardiovascular diseases
cardiovascular risk
health metrics
Publication Status
Published
Coverage Spatial
England
Article Number
ARTN 100022
Date Publish Online
2021-07-26
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