Poly(ethylene dioxythiophene) with functional pendant groups bearing double bonds is synthesized and employed for the fabrication of electroactive hydrogels with advantageous characteristics; covalently crosslinked porous 3D scaffolds with notable swelling ratio, appropriate mechanical properties, electroactive in physiological conditions, and suitable for prolifera-tion and differentiation of C2C12 cells. This is a new approach for the fabrication of conductive engineered constructs.