Short physical performance battery as a predictor of adverse outcomes following hospitalisation for an acute exacerbation of COPD
File(s)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Background: Hospitalisation for acute exacerbations of COPD (AECOPD) is associated with increased mortality, and high risk of readmission. The Short Physical Performance Battery (SPPB), a composite index of 3 lower extremity physical performance measures (score 0-12), is a consistent predictor of adverse outcomes in the geriatric population.
Hypothesis: SPPB measured at discharge predicts risk of readmission and death at 1 year in patients hospitalised with AECOPD.
Methods: SPPB was measured in 213 patients hospitalised with an AECOPD. Hospitalisations and vital status were recorded at 1 year.
Results: Baseline characteristics:mean age 72, FEV1 40%pred, 52% male. Mean(SD) SPPB was 6.3(3.1). 52.1% patients were readmitted and 16.4% died during 1 year of follow-up. Patients with low SPPB scores(0-3) at hospital discharge had significantly increased rates of all-cause readmission and mortality compared with those with the highest scores(10-12):(29.7% vs. 10.8%;p=0.004 and 37.1% vs. 5.7%;p<0.001). Low SPPB scores were associated with greater odds of all cause readmission and mortality at 1 year;crude OR(95% CI) 6.14(2.42-15.55) and 7.68(1.62-36.5) respectively). Each one point increase in SPPB score resulted in lower odds of readmission and mortality at 1 year (OR 0.81(0.74-0.90) and 0.81(0.71-0.93) respectively). Gait speed (a component of SPPB) as a single item was equivalent or better than the SPPB in predicting readmission (c-statistic 0.672vs.0.671) and death (0.698vs.0.666) at 1 year.
Conclusion: The SPPB predicts readmission and mortality at 1 year in patients hospitalised with AECOPD, but has no additional prognostic value over its component, gait speed.
Hypothesis: SPPB measured at discharge predicts risk of readmission and death at 1 year in patients hospitalised with AECOPD.
Methods: SPPB was measured in 213 patients hospitalised with an AECOPD. Hospitalisations and vital status were recorded at 1 year.
Results: Baseline characteristics:mean age 72, FEV1 40%pred, 52% male. Mean(SD) SPPB was 6.3(3.1). 52.1% patients were readmitted and 16.4% died during 1 year of follow-up. Patients with low SPPB scores(0-3) at hospital discharge had significantly increased rates of all-cause readmission and mortality compared with those with the highest scores(10-12):(29.7% vs. 10.8%;p=0.004 and 37.1% vs. 5.7%;p<0.001). Low SPPB scores were associated with greater odds of all cause readmission and mortality at 1 year;crude OR(95% CI) 6.14(2.42-15.55) and 7.68(1.62-36.5) respectively). Each one point increase in SPPB score resulted in lower odds of readmission and mortality at 1 year (OR 0.81(0.74-0.90) and 0.81(0.71-0.93) respectively). Gait speed (a component of SPPB) as a single item was equivalent or better than the SPPB in predicting readmission (c-statistic 0.672vs.0.671) and death (0.698vs.0.666) at 1 year.
Conclusion: The SPPB predicts readmission and mortality at 1 year in patients hospitalised with AECOPD, but has no additional prognostic value over its component, gait speed.
Date Issued
2016-09-01
Date Acceptance
2016-09-01
Citation
European Respiratory Journal, 2016, 48 (suppl 60)
ISSN
0903-1936
Publisher
European Respiratory Society
Journal / Book Title
European Respiratory Journal
Volume
48
Issue
suppl 60
Copyright Statement
© 2016 the authors. This is an author-submitted, peer-reviewed version of a manuscript that has been accepted for publication in the European Respiratory Journal, prior to copy-editing, formatting and typesetting. This version of the manuscript may not be duplicated or reproduced without prior permission from the copyright owner, the European Respiratory Society. The publisher is not responsible or liable for any errors or omissions in this version of the manuscript or in any version derived from it by any other parties. The final, copy-edited, published article, which is the version of record, is available without a subscription 18 months after the date of issue publication.
Source
ERS International Congress 2016
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
COPD - exacerbations
Publication Status
Published
Date Publish Online
2016-11-08