Emerging invasive group A Streptococcus M1UK lineage detected by allele-specific PCR, England, 2020
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Published version
Author(s)
Type
Journal Article
Abstract
Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK. An allele-specific PCR was developed to distinguish M1UK from other emm1 strains. The M1UK lineage represented 91% of invasive emm1 isolates in England in 2020. Allele-specific PCR will permit surveillance for M1UK without need for genome sequencing.
Date Issued
2023-05
Date Acceptance
2023-04-01
Citation
Emerging Infectious Diseases, 2023, 29 (5), pp.1007-1010
ISSN
1080-6040
Publisher
Centers for Disease Control and Prevention
Start Page
1007
End Page
1010
Journal / Book Title
Emerging Infectious Diseases
Volume
29
Issue
5
Copyright Statement
All materials published in Emerging Infectious Diseases, including text, figures, tables, and photographs, are in the public domain and can be reprinted or used without permission with proper citation. All content is freely available without charge to the user or their institution. In accordance with the Budapest Open Access Initiative definition of open access, users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. Because the journal is in the public domain, its usage policy also conforms to conditions set forth by Creative Commons.
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/37019153
Subjects
Alleles
Antigens, Bacterial
Bacterial Outer Membrane Proteins
England
Humans
Polymerase Chain Reaction
Scarlet Fever
Streptococcal Infections
Streptococcus pyogenes
allele-specific
bacteria
emerging lineage
emm1
England
group A Streptococcus
iGAS
M1UK
molecular diagnostics
PCR
respiratory infections
scarlet fever
streptococci
Streptococcus pyogenes
superantigen
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2023-04-05