Iodination of terminal alkynes using KI/CuSO4 – A facile method with potential for radio-iodination
Author(s)
Ferris, Trevor
Carroll, Laurence
Mease, Ronnie C
Spivey, Alan C
Aboagye, Eric O
Type
Journal Article
Abstract
Herein, we report an efficient new method for the iodination of terminal alkynes using stoichiometric KI and CuSO4 in a mix of acetonitrile and acetate buffer that holds promise for further development into a method for radio-iodination.
Date Issued
2019-03-28
Date Acceptance
2019-02-22
Citation
Tetrahedron Letters, 2019, 60 (13), pp.936-939
ISSN
0040-4039
Publisher
Elsevier BV
Start Page
936
End Page
939
Journal / Book Title
Tetrahedron Letters
Volume
60
Issue
13
Copyright Statement
© 2019 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
Sponsor
Cancer Research UK
Grant Number
C2536/A16584
Subjects
0305 Organic Chemistry
Organic Chemistry
Publication Status
Published
Date Publish Online
2019-02-23