Fatty Liver Disease: A Crosstalk Between Lipid Species
File(s)Martinez, 2016.pdf (116.72 KB)
Published version
Author(s)
Martinez-Gili, Laura
Garcia-Ruiz, C
Fernandez-Checa, C
Type
Journal Article
Abstract
The role of different lipid species such as free fatty acids and sphingolipids in non-alcoholic fatty liver disease (NAFLD) has been extensively studied during the last decade. In addition, free cholesterol accumulation in hepatocytes plays a crucial role in the transition from steatosis to steatohepatitis. However, the contribution of these lipids to NAFLD pathology is often evaluated individually. This review attempts to enclose the main metabolic and signalling connections between lipotoxic lipid species, and how their homeostasis is disrupted in NAFLD.
Date Issued
2016-05-31
Date Acceptance
2016-05-04
Citation
European Medical Journal: Hepatology, 2016, 4 (1), pp.76-83
Publisher
Gorely New Media
Start Page
76
End Page
83
Journal / Book Title
European Medical Journal: Hepatology
Volume
4
Issue
1
Copyright Statement
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
Identifier
https://www.emjreviews.com/hepatology/article/fatty-liver-disease-a-crosstalk-between-lipid-species/
Publication Status
Published