The Gediz (Alaşehir) Graben is located in the highly tectonically active and seismogenic region of Western Turkey. The rivers upstream of the normal fault-bounded graben each contain a non-lithologic knickpoint, including those that drain through inferred fault segment boundaries. Knickpoint heights measured vertically from the fault scale with footwall relief and documented fault throw (vertical displacement). Consequently, we deduce these knickpoints were initiated by an increase in slip rate on the basin-bounding fault, driven by linkage of the three main fault segments of the high-angle graben bounding fault array. Fault interaction theory and ratios of channel steepness suggest that the slip rate enhancement factor on linkage was a factor of 3. We combine this information with geomorphic and structural constraints to estimate that linkage took place between 0.6 Ma and 1 Ma. Calculated pre- and post-linkage throw rates are 0.6 and 2 mm/yr respectively. Maximum knickpoint retreat rates upstream of the faults range from 4.5 to 28 mm/yr, faster than for similar catchments upstream of normal faults in the Central Apennines and the Hatay Graben of Turkey, and implying a fluvial landscape response time of 1.6 to 2.7 Myr. We explore the relative controls of drainage area and precipitation on these retreat rates, and conclude that while climate variation and fault throw rate partially explain the variations seen, lithology remains a potentially important but poorly characterised variable.