Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens
Author(s)
Dart, DA
Brooke, GN
Sita-Lumsden, A
Waxman, J
Bevan, CL
Type
Journal Article
Date Issued
2012-10-01
ISSN
0950-9232
Publisher
NATURE PUBLISHING GROUP
Start Page
4588
End Page
4598
Journal / Book Title
ONCOGENE
Volume
31
Issue
43
Copyright Statement
Copyright © 2011, Rights Managed by Nature Publishing Group
Sponsor
Medical Research Council (MRC)
Cancer Research UK
Prostate Cancer UK
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310528200002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
G0700915
12196
PG10-25
Subjects
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Oncology
Cell Biology
Genetics & Heredity
BIOCHEMISTRY & MOLECULAR BIOLOGY
CELL BIOLOGY
GENETICS & HEREDITY
ONCOLOGY
prohibitin
androgen receptor
prostate
androgens
castrate-resistant prostate cancer
corepressor
TRANSCRIPTIONAL REPRESSION
CANCER CELLS
NUCLEUS
PROTEIN
RAT
SUPERFAMILY
RECRUITMENT
SUPPRESSION
PROGRESSION
SENESCENCE
Acetylation
Adrenal Glands
Androgens
Female
Gene Knockdown Techniques
Histones
Humans
Male
Promoter Regions, Genetic
Prostatic Neoplasms
Protein Binding
Receptors, Androgen
Repressor Proteins
1112 Oncology And Carcinogenesis
1103 Clinical Sciences
Oncology & Carcinogenesis
Publication Status
Published