Real time complete Stokes polarimetric imager based on a linear polarizer array camera for tissue polarimetric imaging
File(s)boe-8-11-4933.pdf (7.41 MB)
Published version
Author(s)
Qi, J
He, C
Elson, DS
Type
Journal Article
Abstract
Tissue polarimetric imaging measures Mueller matrices of tissues or Stokes vectors of the emergent light from tissues (normally using incidence with a fixed polarization state) over a field of view, and has demonstrated utility in a number of surgical and diagnostic applications. Here we introduce a compact complete Stokes polarimetric imager that can work for multiple wavelength bands with a frame-rate suitable for real-time applications. The imager was validated with standard polarizing components, and then employed as a polarization state analyzer of a Mueller imaging polarimeter and a standalone Stokes imaging polarimeter respectively to image the process of dehydration of bovine tendon tissue. The results obtained in this work suggested that the polarization properties of the samples rich of collagen fibres can change with the degree of dehydration, and therefore, dehydration of the samples prepared for polarimetric imaging (e.g. polarimetric microscopy) should be carefully controlled.
Date Issued
2017-10-10
Date Acceptance
2017-10-03
Citation
Biomedical Optics Express, 2017, 8 (11), pp.4933-4949
ISSN
2156-7085
Publisher
Optical Society of America
Start Page
4933
End Page
4949
Journal / Book Title
Biomedical Optics Express
Volume
8
Issue
11
Copyright Statement
Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.
License URL
Sponsor
Commission of the European Communities
National Institute for Health Research
Identifier
https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-8-11-4933&id=375124
Grant Number
242991
II-LB-0214-20009
Subjects
Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemical Research Methods
Optics
Radiology, Nuclear Medicine & Medical Imaging
Biochemistry & Molecular Biology
MUELLER MATRIX POLARIMETRY
BIOLOGICAL TISSUES
PHOTOELASTIC MODULATORS
CANCEROUS TISSUES
LIGHT
DIAGNOSIS
MICROSTRUCTURES
SPECTROSCOPY
CALIBRATION
MICROSCOPE
(120.5410) Polarimetry
(170.6935) Tissue characterization
0205 Optical Physics
0912 Materials Engineering
Publication Status
Published
Date Publish Online
2017-10-10