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Improving Dengue diagnostics and management through innovative technology
File(s)
Rodriguez-Manzano_et_al-2018-Current_Infectious_Disease_Reports.pdf (1 MB)
Published version
Author(s)
Rodriguez-Manzano, Jesus
Ying Chia, Po
Wen Yeo, Tsin
Holmes, AH
Georgiou, Pantelis
more
Type
Journal Article
Abstract
Purpose of Review:

Dengue continues to be a major global public health threat. Symptomatic infections can cause a spectrum of disease ranging from a mild febrile illness to severe and potentially life-threatening manifestations. Management relies on supportive treatment with careful fluid replacement. The purpose of this review is to define the unmet needs and challenges in current dengue diagnostics and patient monitoring and outline potential novel technologies to address these needs.
Recent Findings:

There have been recent advances in molecular and point-of-care (POC) diagnostics as well as technologies including wireless communication, low-power microelectronics, and wearable sensors that have opened up new possibilities for management, clinical monitoring, and real-time surveillance of dengue.
Summary:

Novel platforms utilizing innovative technologies for POC dengue diagnostics and wearable patient monitors have the potential to revolutionize dengue surveillance, outbreak response, and management at population and individual levels. Validation studies of these technologies are urgently required in dengue-endemic areas.
Date Issued
2018-08-01
Date Acceptance
2018-03-01
Citation
Current Infectious Disease Reports, 2018, 20 (August 2018 20:25)
URI
http://hdl.handle.net/10044/1/59980
DOI
https://www.dx.doi.org/10.1007/s11908-018-0633-x
ISSN
1534-3146
Publisher
Springer
Journal / Book Title
Current Infectious Disease Reports
Volume
20
Issue
August 2018 20:25
Copyright Statement
© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Sponsor
National Institute for Health Research
National Institute for Health Research
National Institute for Health Research
National Institute for Health Research
Grant Number
HPRU-2012-10047
HPRU-2012-10047
II-LA-0214-20008
II-LA-0214-20008
Subjects
Microbiology
Publication Status
Published
Article Number
ARTN 25
Date Publish Online
2018-06-07
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