Off-pump CABG is a safe option during pregnancy, where cardiopulmonary bypass (CPB) could pose additional significant surgical risk
Author(s)
Hasanzade, Sahar
Ortac, Alev
Alkassar, Alkassar
Theodoropoulos, Panagiotis
Al Jaaly, Emad
Type
Journal Article
Abstract
Off-pump coronary artery bypass grafting (OPCAB) is a surgical technique designed to treat coronary artery disease (CAD) by restoring blood flow to the myocardium through new arterial or venous grafts without the use of cardiopulmonary bypass (CPB). The gold standard
conduit, the left internal thoracic artery (LITA), is most commonly anastomosed to the distal left anterior descending (LAD) artery [1], with additional grafts based on anatomical requirements [1,2]. OPCAB offers distinct advantages over traditional on-pump CABG, notably reducing complications such as systemic inflammatory response, neurological deficits, and prolonged recovery [1,2]. It is particularly beneficial in patients at high risk for
stroke [3] or renal failure [4].
We report a rare case of successful OPCAB in a 27-year-old pregnant woman with homozygous familial hypercholesterolemia (FH) and multivessel CAD during her second trimester. This case underscores the feasibility, safety, and effectiveness of OPCAB in managing complex coronary disease during pregnancy, minimizing maternal and fetal risks associated with CPB.
conduit, the left internal thoracic artery (LITA), is most commonly anastomosed to the distal left anterior descending (LAD) artery [1], with additional grafts based on anatomical requirements [1,2]. OPCAB offers distinct advantages over traditional on-pump CABG, notably reducing complications such as systemic inflammatory response, neurological deficits, and prolonged recovery [1,2]. It is particularly beneficial in patients at high risk for
stroke [3] or renal failure [4].
We report a rare case of successful OPCAB in a 27-year-old pregnant woman with homozygous familial hypercholesterolemia (FH) and multivessel CAD during her second trimester. This case underscores the feasibility, safety, and effectiveness of OPCAB in managing complex coronary disease during pregnancy, minimizing maternal and fetal risks associated with CPB.
Date Acceptance
2025-05-06
Citation
Frontiers in Surgery: Cardiovascular Surgery
ISSN
2296-875X
Journal / Book Title
Frontiers in Surgery: Cardiovascular Surgery
Copyright Statement
Subject to copyright. This paper is embargoed until publication. Once published the Version of Record (VoR) will be available on immediate open access.
Publication Status
Accepted