Transition from neonatal to paediatric intensive care of very preterm-born children: a cohort study of children born 2013-2018 in England and Wales
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Accepted version
Author(s)
Type
Journal Article
Abstract
Objective
Following very preterm birth, some children require ongoing intensive care after the neonatal period and transition directly from neonatal units (NNUs) to paediatric intensive care units (PICUs) around term-corrected age.
We aimed to understand, at a national level, characteristics and outcomes of children born very preterm who transitioned directly from NNUs to PICUs.
Design
Retrospective cohort study, using data linkage of National Neonatal Research Database, Paediatric Intensive Care Audit Network (PICANet), and Office for National Statistics datasets.
Setting
All NNUs and PICUs in England and Wales.
Patients
Children born <32 gestational weeks between 1/1/2013 and 31/12/2018, admitted to NNUs and who transitioned directly to PICU without return to NNU at ≥36 weeks corrected gestation age.
Main outcome measures
Mortality, length of PICU stay, invasive ventilation in PICU (including via tracheostomy), PICU readmission until two years of age.
Results
Direct NNU to PICU transitions occurred in 276 babies during the study period. An increasing yearly trend was observed: 36 transitions of babies born in 2013, 65 in 2018.
Of this cohort, 22% of children died before their second birthday, 59% of survivors had ≥1 PICU readmission, 33% of children had long-stays in PICU (≥28 days) and 25% received tracheostomy ventilation.
Conclusions
An increasing number of very preterm children require ongoing intensive care at the end of their neonatal stay, with high mortality and morbidity. Multidisciplinary involvement and planning around the time of transition from NNU to PICU, informed by national guidance, may be beneficial.
Following very preterm birth, some children require ongoing intensive care after the neonatal period and transition directly from neonatal units (NNUs) to paediatric intensive care units (PICUs) around term-corrected age.
We aimed to understand, at a national level, characteristics and outcomes of children born very preterm who transitioned directly from NNUs to PICUs.
Design
Retrospective cohort study, using data linkage of National Neonatal Research Database, Paediatric Intensive Care Audit Network (PICANet), and Office for National Statistics datasets.
Setting
All NNUs and PICUs in England and Wales.
Patients
Children born <32 gestational weeks between 1/1/2013 and 31/12/2018, admitted to NNUs and who transitioned directly to PICU without return to NNU at ≥36 weeks corrected gestation age.
Main outcome measures
Mortality, length of PICU stay, invasive ventilation in PICU (including via tracheostomy), PICU readmission until two years of age.
Results
Direct NNU to PICU transitions occurred in 276 babies during the study period. An increasing yearly trend was observed: 36 transitions of babies born in 2013, 65 in 2018.
Of this cohort, 22% of children died before their second birthday, 59% of survivors had ≥1 PICU readmission, 33% of children had long-stays in PICU (≥28 days) and 25% received tracheostomy ventilation.
Conclusions
An increasing number of very preterm children require ongoing intensive care at the end of their neonatal stay, with high mortality and morbidity. Multidisciplinary involvement and planning around the time of transition from NNU to PICU, informed by national guidance, may be beneficial.
Date Acceptance
2024-11-14
Citation
Archives of Disease in Childhood: Fetal and Neonatal Edition
ISSN
1359-2998
Publisher
BMJ Publishing Group
Journal / Book Title
Archives of Disease in Childhood: Fetal and Neonatal Edition
Copyright Statement
Subject to copyright. This paper is embargoed until publication. Once published the author’s accepted manuscript will be made available under a CC-BY License in accordance with Imperial’s Research Publications Open Access policy (www.imperial.ac.uk/oa-policy).
License URL
Publication Status
Accepted
Rights Embargo Date
10000-01-01