The cost of hospital care for management of invasive group A streptococcal infections in England
File(s)
Accepted version
Author(s)
Hughes, GJ
Van Hoek, AJ
Sriskandan, S
Lamagni, TL
Type
Journal Article
Abstract
The objective of this study was to estimate the direct financial costs of hospital care for management of invasive group A streptococcal (GAS) infections using hospital records for cases diagnosed in England. We linked laboratory-confirmed cases (n = 3696) identified through national surveillance to hospital episode statistics and reimbursement codes. From these codes we estimated the direct hospital costs of admissions. Almost all notified invasive GAS cases (92% of 3696) were successfully matched to a primary hospital admission. Of these, secondary admissions (within 30 days of primary admission) were further identified for 593 (17%). After exclusion of nosocomial cases (12%), the median costs of primary and secondary hospital admissions were estimated by subgroup analysis as £1984–£2212 per case, totalling £4·43–£6·34 million per year in England. With adjustment for unmatched cases this equated to £4·84–£6·93 million per year. Adults aged 16–64 years accounted for 48% of costs but only 40% of cases, largely due to an increased number of surgical procedures. The direct costs of hospital admissions for invasive GAS infection are substantial. These estimated costs will contribute to a full assessment of the total economic burden of invasive GAS infection as a means to assess potential savings through prevention measures.
Date Issued
2015-09-29
Date Acceptance
2014-08-27
Citation
EPIDEMIOLOGY AND INFECTION, 2015, 143 (8), pp.1719-1730
ISSN
0950-2688
Publisher
CAMBRIDGE UNIV PRESS
Start Page
1719
End Page
1730
Journal / Book Title
EPIDEMIOLOGY AND INFECTION
Volume
143
Issue
8
Copyright Statement
The final publication is available via Cambridge Journals Online at https://dx.doi.org/10.1017/S0950268814002489
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000354061100020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Public, Environmental & Occupational Health
Infectious Diseases
Cost of disease
hospital costs
streptococcal infections
Streptococcus pyogenes
treatment costs
VACCINE IMPLICATIONS
HIGH-RISK
DISEASE
EPIDEMIOLOGY
BURDEN
ROTAVIRUS
PROPHYLAXIS
CHILDREN
INFANTS
IMPACT
Publication Status
Published