Tonsillar carcinoma spreading metastases to central nervous system –
Case report and literature review
Case report and literature review
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
We present a case report of a 51-year-old left-handed gentleman with a background of HPV 16-positive tonsil squamous cell carcinoma presenting with tonic-clonic seizure and a radiological diagnosis of secondary metastatic deposits. These were initially treated with Stereotactic RadioSurgery (SRS), and subsequently with surgery. Surgical resection was performed under general anaesthesia with right-sided temporal and parietal approaches. Both the parietal and temporal deposits were removed, while the intraventricular mass was
intentionally left to avoid post-op deficits. Adjuvant radiotherapy and chemotherapy were administered post-op. The patient experienced a satisfactory recovery post-op and was re-operated for recurrence 4 months later. He maintained a good quality of life and an excellent performance status throughout, but unfortunately passed away in November 2018 due to septic complications. This case history stresses the difficulty in managing SCC with brain metastatic deposits. There are no current guidelines about the management of patients presenting with such a rare condition. More data is thus desirable in order to better define
treatment guidelines and protocols when SCC brain metastases are present.
intentionally left to avoid post-op deficits. Adjuvant radiotherapy and chemotherapy were administered post-op. The patient experienced a satisfactory recovery post-op and was re-operated for recurrence 4 months later. He maintained a good quality of life and an excellent performance status throughout, but unfortunately passed away in November 2018 due to septic complications. This case history stresses the difficulty in managing SCC with brain metastatic deposits. There are no current guidelines about the management of patients presenting with such a rare condition. More data is thus desirable in order to better define
treatment guidelines and protocols when SCC brain metastases are present.
Date Issued
2021-06-14
Date Acceptance
2020-11-17
Citation
Journal of Neurological Surgery Reports, 2021, 82 (02), pp.e11-e16
ISSN
2193-6358
Publisher
Thieme Open
Start Page
e11
End Page
e16
Journal / Book Title
Journal of Neurological Surgery Reports
Volume
82
Issue
02
Copyright Statement
© 2021. The Author(s).
This is an open access article published by Thieme under the terms of the
Creative Commons Attribution-NonDerivative-NonCommercial-License,
permitting copying and reproduction so long as the original work is given
appropriate credit. Contents may not be used for commercial purposes, or
adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
This is an open access article published by Thieme under the terms of the
Creative Commons Attribution-NonDerivative-NonCommercial-License,
permitting copying and reproduction so long as the original work is given
appropriate credit. Contents may not be used for commercial purposes, or
adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Sponsor
Brain Tumour Research
Identifier
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0041-1726305
Subjects
Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Neurosciences & Neurology
central nervous system metastasis
tonsillar squamous cell carcinoma
neurosurgery
oncology
SQUAMOUS-CELL CARCINOMA
ADVANCED OROPHARYNX CANCER
LYMPH-NODE METASTASES
HUMAN-PAPILLOMAVIRUS
DISTANT METASTASES
POSITIVE TONSILLAR
NECK-CANCER
HEAD
TRENDS
EPIDEMIC
central nervous system metastasis
neurosurgery
oncology
tonsillar squamous cell carcinoma
Publication Status
Published
Date Publish Online
2021-06-14