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Technical Development of a New Semispherical Radiofrequency Bipolar Device (RONJA): Ex Vivo and In Vivo Studies
File(s)
Author(s)
Vavra, P
Penhaker, M
Grepl, J
Jurcikova, J
Palecek, J
Type
Journal Article
Abstract
The aim of this study is to inform about the development of a new semispherical surgical instrument for the bipolar multielectrode radiofrequency liver ablation. Present tools are universal; however they have several disadvantages such as ablation of healthy tissue, numerous needle punctures, and, therefore, longer operating procedure. Our newly designed and tested semispherical surgical tool can solve some of these disadvantages. By conducting an in vivo study on a set of 12 pigs, randomly divided into two groups, we have compared efficiency of the newly developed instrument with the commonly used device. Statistical analysis showed that there were no significant differences between the groups. On average, the tested instrument RONJA had shorter ablation time in both liver lobes and reduced the total operating time. The depth of the thermal alteration was on average 4 mm larger using the newly tested instrument. The new radiofrequency method described in this study could be used in open liver surgery for the treatment of small liver malignancies (up to 2 cm) in a single application with the aim of saving healthy liver parenchyma. Further experimental studies are needed to confirm these results before clinical application of the method in the treatment of human liver malignancies.
Date Issued
2014-04-09
Date Acceptance
2014-03-04
Citation
BioMed Research International, 2014, 2014
URI
DOI
ISSN
2314-6141
Publisher
Hindawi Publishing Corporation
Journal / Book Title
BioMed Research International
Volume
2014
Copyright Statement
© 2014 Petr Vavra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
License URL
Subjects
Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
Medicine, Research & Experimental
Research & Experimental Medicine
LIVER
RESECTION
ABLATION
Animals
Biopsy
Catheter Ablation
Electrodes
In Vitro Techniques
Liver
Sus scrofa
Thermography
Publication Status
Published
Article Number
532792