A joint modelling of socio-professional trajectories and cause-specific mortality
File(s)Karimi_CSDA_2ndRevised_Version.pdf (496.21 KB)
Accepted version
Author(s)
Karimi, M
Rey, G
Latouche, A
Type
Journal Article
Abstract
The association between life-course socio-professional trajectories and mortality has already been discussed in the literature. However, these socio-professional trajectories may be subject to informative censoring due to death. This loss to follow-up which is related to an individual’s survival, should not be ignored and thus, it is of interest to model jointly these professional trajectories and their survival. The main focus has been made on continuous, binary or ordinal variables while much less attention has been paid to nominal categorical data. Therefore, an extension to the joint modelling of longitudinal nominal data and survival under a likelihood-based approach is proposed. A generalized linear mixed model is considered for modelling the longitudinal nominal data, in addition to two cause-specific proportional hazards model for the survival competing risks data. The association between longitudinal and survival outcomes is captured by assuming a multivariate Gaussian distribution for the joint distribution of the random effects of two sub-models. The proposed joint model provides a robust framework for estimating longitudinal membership probabilities, accounting for informative censoring caused by individual’s death. Simulations are carried out to assess the performance of this joint model comparing with the results of the separate longitudinal and competing risks analysis. A disadvantage of joint models is that they are computationally intensive. To overcome this problem, an approach mimicking a meta-analysis strategy of individual participant data is suggested. The relevance of this approach is then illustrated on a large sample of the French salaried population, which contains all employment records between 1976 and 2002.
Date Issued
2018-03-01
Date Acceptance
2017-10-07
Citation
Computational Statistics and Data Analysis, 2018, 119, pp.39-54
ISSN
0167-9473
Publisher
Elsevier
Start Page
39
End Page
54
Journal / Book Title
Computational Statistics and Data Analysis
Volume
119
Copyright Statement
© 2017 Elsevier B.V. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418970900003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Technology
Physical Sciences
Computer Science, Interdisciplinary Applications
Statistics & Probability
Computer Science
Mathematics
Generalized linear mixed model
Cause-specific hazards
Joint model
Membership probability
Large-scale data
COMPETING RISKS
LONGITUDINAL DATA
SURVIVAL-DATA
TIME
FRANCE
Publication Status
Published
Date Publish Online
2017-10-18