Population-based approaches to Alzheimer's disease prevention.
File(s)
Accepted version
Author(s)
Perneczky, Robert
Type
Chapter
Abstract
Progress in prevention and treatment of Alzheimer's disease (AD) and dementia is hampered by the restricted understanding of the biological and environmental causes underlying pathophysiology. It is widely accepted that certain genetic factors are associated with AD and a number of lifestyle and other environmental characteristics have also been linked to dementia risk. However, interactions between genes and the environment are not yet well understood, and coordinated global action is required to utilize existing cohorts and other resources effectively and efficiently to identify new avenues for dementia prevention. This chapter provides a brief summary of current research on risk and protective factors and opportunities and challenges in relation to population-based approaches are discussed.
Editor(s)
Perneczky, Robert
Date Issued
2018-03-07
Citation
Biomarkers for Alzheimer’s Disease Drug Development, 2018, 1750, pp.15-29
Publisher
Springer
Start Page
15
End Page
29
Journal / Book Title
Biomarkers for Alzheimer’s Disease Drug Development
Methods in Molecular Biology
Volume
1750
Copyright Statement
© Springer Science+Business Media, LLC 2018. The final publication is available at Springer via [insert hyperlinked DOI]
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/29512063
Subjects
Alzheimer’s disease
Cohort studies
Dementia
Drug development
Environment
Genetics
Lifestyle
Population-based
Alzheimer Disease
Genetic Predisposition to Disease
Humans
Preventive Medicine
Risk Factors
Publication Status
Published
Date Publish Online
2018-03-07