"Congenital cytomegalovirus in Sub-Saharan Africa-a narrative review with practice recommendations"
File(s)fpubh-12-1359663.pdf (1.02 MB)
Published version
Author(s)
Payne, H
Barnabas, S
Type
Journal Article
Abstract
Cytomegalovirus (CMV) is the most common cause of congenital infection internationally, occurring in 0.67% of births, and increasingly recognised as a major public health burden due to the potential for long-term neurodevelopmental and hearing impairment. This burden includes estimates of 10% of childhood cerebral palsy and up to 25% of childhood deafness. In Sub-Saharan Africa, where CMV-seroprevalence is almost ubiquitous, prevalence of congenital CMV (cCMV) is higher than the global average, and yet there is a dearth of research and initiatives to improve recognition, diagnosis and treatment. This narrative review outlines the epidemiology and clinical presentation of cCMV, discusses issues of case identification and treatment in Sub-Saharan Africa, and recommends a framework of strategies to address these challenges. Considering the significant burden of cCMV disease in this setting, it is undoubtably time we embark upon improving diagnosis and care for these infants.
Date Issued
2024-05-15
Online Publication Date
2024-06-11T15:19:20Z
Date Acceptance
2024-04-24
ISSN
2296-2565
Publisher
Frontiers Media S.A.
Journal / Book Title
Frontiers in Public Health
Volume
12
Copyright Statement
Copyright © 2024 Payne and Barnabas. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
License URI
Identifier
https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1359663/full
https://www.ncbi.nlm.nih.gov/pubmed/38813410
Publication Status
Published
Country
Switzerland
Article Number
1359663
Date Publish Online
2024-05-15