Identification and Characterization of PERK Activators by Phenotypic Screening and Their Effects on NRF2 Activation

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Author(s)

Xie, W

Pariollaud, M

Wixted, WE

Chitnis, N

Fornwald, J

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Type

Journal Article

Date Issued

2015-03-17

URI

http://hdl.handle.net/10044/1/54073

DOI

https://dx.doi.org/10.1371/journal.pone.0119738

ISSN

1932-6203

Publisher

PUBLIC LIBRARY SCIENCE

Journal / Book Title

PLOS ONE

Volume

10

Issue

3

Copyright Statement

© 2015 Xie et al. This is an open access
article distributed under the terms of the Creative
Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any
medium, provided the original author and source are
credited.

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351284600086&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Subjects

Science & Technology

Multidisciplinary Sciences

Science & Technology - Other Topics

ENDOPLASMIC-RETICULUM STRESS

UNFOLDED PROTEIN RESPONSE

CIGARETTE-SMOKE

CELL-SURVIVAL

MOLECULAR-MECHANISMS

GENE-REGULATION

PATHWAY

DISEASE

CANCER

DYSFUNCTION

Animals

Cells, Cultured

Endoplasmic Reticulum Stress

Eukaryotic Initiation Factor-2

Green Fluorescent Proteins

High-Throughput Screening Assays

Homeostasis

Mice

NF-E2-Related Factor 2

Phenotype

Phosphorylation

Protein Biosynthesis

Signal Transduction

Small Molecule Libraries

Thapsigargin

eIF-2 Kinase

MD Multidisciplinary

General Science & Technology

Publication Status

Published

Article Number

ARTN e0119738