Designing new eco-friendly fibers enable the creation of an alternative resource for many applications, specifically within the field of polymeric composites. This article details the fabrication of hybrid epoxy composites comprising natural fiber, Phoenix pusilla plant dry leaves which belong to the family of date palm and nanofillers made from the fish bones, which has been explored for the first time. ASTM standards provided the guidelines for the preparation of samples and mechanical measurements. The mechanical properties of the pure carbon fiber composites were compared with that of the hybrid composites containing carbon fiber, natural fiber and nanofiller. The results validate the potential of hybrid composites containing novel fibers. Adding the bio-nanofillers in hybrid polymer composites permits the enhancement of the tensile strength, flexural strength, and hardness by 22.5, 200, 100 and 15.2%, respectively.