Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for cardiovascular diseases and diabetes: Airwave Health Monitoring Study
File(s) DRV paper.docx (119.59 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
CVD is the leading cause of death worldwide. Diet is a key modifiable component in the development of CVD. No official UK diet quality index exists for use in UK nutritional epidemiological studies. The aims of this study are to: (i) develop a diet quality index based on components of UK dietary reference values (DRV) and (ii) determine the association between the index, the existing UK nutrient profile (NP) model and a comprehensive range of cardiometabolic risk markers among a British adult population. A cross-sectional analysis was conducted using data from the Airwave Health Monitoring Study (n 5848). Dietary intake was measured by 7-d food diary and metabolic risk using waist circumference, BMI, blood lipid profile, glycated Hb (HbA1c) and blood pressure measurements. Diet quality was assessed using the novel DRV index and NP model. Associations between diet and cardiometabolic risk were analysed via multivariate linear models and logistic regression. A two-point increase in NP score was associated with total cholesterol (β −0·33 mmol/l, P<0·0001) and HbA1c (β −0·01 %, P<0·0001). A two-point increase in DRV score was associated with waist circumference (β −0·56 cm, P<0·0001), BMI (β −0·15 kg/m2, P<0·0001), total cholesterol (β −0·06 mmol/l, P<0·0001) and HbA1c (β −0·02 %, P=0·002). A one-point increase in DRV score was associated with type 2 diabetes (T2D) (OR 0·94, P=0·01) and obesity (OR 0·95, P<0·0001). The DRV index is associated with overall diet quality and risk factors for CVD and T2D, supporting its application in nutritional epidemiological studies investigating CVD risk in a UK population.
Date Issued
2018-03-28
Date Acceptance
2017-12-12
Citation
British Journal of Nutrition, 2018, 119 (6), pp.695-705
ISSN
1475-2662
Publisher
Cambridge University Press (CUP)
Start Page
695
End Page
705
Journal / Book Title
British Journal of Nutrition
Volume
119
Issue
6
Copyright Statement
© The Authors 2018. This paper has been accepted for publication and will appear in a revised form, subsequent to peer-review and/or editorial input by Cambridge University Press.
Sponsor
Home Office
Medical Research Council (MRC)
National Institute for Health Research
Public Health England
Imperial College Healthcare NHS Trust- BRC Funding
UK DRI Ltd
Grant Number
7370192
MR/L01341X/1
RTJ6219303-1
6509268
RDF03
N/A
Subjects
Science & Technology
Life Sciences & Biomedicine
Nutrition & Dietetics
Diet quality
Nutrient profile
Type 2 diabetes
CVD
CORONARY-HEART-DISEASE
MEDITERRANEAN DIET
BLOOD-PRESSURE
NUTRITIONAL EPIDEMIOLOGY
WEIGHED RECORDS
QUALITY INDEX
PATTERNS
COHORT
VALIDATION
MORTALITY
BP blood pressure
DRV dietary reference value
HbA1c glycated Hb
NP nutrient profile
SBP systolic BP
T2D type 2 diabetes
TEI total energy intake
0702 Animal Production
1111 Nutrition And Dietetics
0908 Food Sciences
Publication Status
Published
Date Publish Online
2018-02-19
