Self-assembled 2D Free-Standing Janus Nanosheets with Single-Layer Thickness
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
We report the thermodynamically controlled growth of solution-processable and free-standing nanosheets via peptide assembly in two dimensions. By taking advantage of self-sorting between peptide β-strands and hydrocarbon chains, we have demonstrated the formation of Janus 2D structures with single-layer thickness, which enable a predetermined surface heterofunctionalization. A controlled 2D-to-1D morphological transition was achieved by subtly adjusting the intermolecular forces. These nanosheets provide an ideal substrate for the engineering of guest components (e.g., proteins and nanoparticles), where enhanced enzyme activity was observed. We anticipate that sequence-specific programmed peptides will offer promise as design elements for 2D assemblies with face-selective functionalization.
Date Issued
2017-09-13
Date Acceptance
2017-09-04
Citation
Journal of the American Chemical Society, 2017, 139 (39), pp.13592-13595
ISSN
1520-5126
Publisher
American Chemical Society
Start Page
13592
End Page
13595
Journal / Book Title
Journal of the American Chemical Society
Volume
139
Issue
39
Copyright Statement
This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
License URL
Sponsor
Commission of the European Communities
Engineering & Physical Science Research Council (E
Biotechnology and Biological Sciences Research Council (BBSRC)
Engineering & Physical Science Research Council (EPSRC)
Commission of the European Communities
Commission of the European Communities
Grant Number
PIEF_GA-2010-275433
EP/K031953/1
BB/L015129/1
EP/K020641/1
ERC-2013-CoG-616417
660757
Subjects
03 Chemical Sciences
General Chemistry
Publication Status
Published online