Multi-biobank summary data Mendelian randomisation
does not support a causal effect of IL-6 signalling on risk
of pulmonary arterial hypertension
does not support a causal effect of IL-6 signalling on risk
of pulmonary arterial hypertension
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
In the most comprehensive analysis to date, this study failed to detect an association of genetically predicted CRP-weighted IL-6 signalling or CRP-weighted IL-6R signalling with PAH risk using all available PAH GWAS data https://bit.ly/3T5h5uj
Date Issued
2024-04
Date Acceptance
2024-02-14
Citation
European Respiratory Journal, 2024, 63 (4)
ISSN
0903-1936
Publisher
European Respiratory Society
Journal / Book Title
European Respiratory Journal
Volume
63
Issue
4
Copyright Statement
Copyright ©The authors 2024.
This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
License URL
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/38453257
Subjects
Biological Specimen Banks
Familial Primary Pulmonary Hypertension
Genome-Wide Association Study
Humans
Interleukin-6
Polymorphism, Single Nucleotide
Pulmonary Arterial Hypertension
Risk Factors
Publication Status
Published
Coverage Spatial
England
Article Number
2302031
Date Publish Online
2024-04-04