Energy systems integration, or sector coupling, has several drivers that span climate impact mitigation and economics to social and regulatory considerations. A key question is what is sector coupling, and how does it impact the flexibility of the energy system? Here, the energy system includes several sectors - electricity, gas, heat, and transportation - that have been independent for decades in most countries except for their coupling via combined heat and power (CHP) units. In energy systems integration, some sectors may provide flexibility to other sectors, while other sectors will require flexibility when interlinking. To support these synergies among sectors, it is important to explore and quantify mutual interactions as well as seek examples of how these integrations can provide flexibility and other benefits. From the perspective of the electricity sector, it is important to ensure that there is enough flexibility in the interconnected systems to support decarbonization goals, such as those set in the Paris Agreement, while ensuring operational reliability.