Tbx18 and the generation of a biological pacemaker. Are we there yet?
File(s)
Published version
Accepted version
Author(s)
Brand, T
Type
Journal Article
Abstract
A group of approximately 10,000 cells in the sinoatrial node (SAN), which is located at the entry of the right superior caval vein into the right atrium, is responsible for regular heart beating under different physiological conditions [1]. While the SAN is reliably working for most of our life, in the elderly, sick sinus syndrome (SSS), or sinus node dysfunction (SND) is prevalent [2] and responsible for 30 to 50% of all electronic pacemaker implantations [3]. Moreover, SSS is also often associated with the development of atrial fibrillation [4].
Date Issued
2016-06-10
Date Acceptance
2016-06-09
Citation
Journal of Molecular and Cellular Cardiology, 2016, 97, pp.263-265
ISSN
1095-8584
Publisher
Elsevier
Start Page
263
End Page
265
Journal / Book Title
Journal of Molecular and Cellular Cardiology
Volume
97
Copyright Statement
© 2016 Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
License URL
Sponsor
British Heart Foundation
British Heart Foundation
Grant Number
PG/14/46/30911
PG/14/83/31128
Subjects
Cardiovascular System & Hematology
1102 Cardiovascular Medicine And Haematology
Publication Status
Published