ASKing no more: the emerging role of DUSP12 in the regulation of hepatic lipid metabolism
File(s)HEP-19-0840-R1_Manuscript.pdf (4.19 MB)
Accepted version
Author(s)
Bubici, Concetta
Lepore, Alessio
Papa, Salvatore
Type
Journal Article
Abstract
Accumulation of fat in liver cells not due to alcohol abuse is the hallmark of non-alcoholic fatty liver disease (NAFLD), a common condition that may progress to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation.(1) Over a long period of time, NASH may lead to fibrosis with consequent cirrhosis, which in turn predisposes patients to hepatocellular carcinoma.
Date Issued
2019-10-01
Date Acceptance
2019-07-07
Citation
Hepatology, 2019, 70 (4), pp.1091-1094
ISSN
0270-9139
Publisher
Wiley
Start Page
1091
End Page
1094
Journal / Book Title
Hepatology
Volume
70
Issue
4
Copyright Statement
© 2019 Owner. This is the accepted version of the following article: Bubici, C. , Lepore, A. and Papa, S. (2019), ASKing no more: the emerging role of DUSP12 in the regulation of hepatic lipid metabolism. Hepatology. Accepted Author Manuscript. doi:10.1002/hep.30851, which has been published in final form at https://doi.org/10.1002/hep.30851.
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/31299103
Subjects
ASK1
hepatic lipid metabolism
mitogen-activated protein kinase
nonalcoholic fatty liver disease
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2019-07-12