45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering
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Published version
Author(s)
Type
Journal Article
Abstract
Highly porous 45S5 bioactive glass-based scaffolds prepared by foam replication method were coated with cellulose nanowhiskers by dip coating method. The obtained cellulose nanowhisker-coated scaffolds retained the high porosity and interconnected pore structure. The cellulose coating improved the mechanical properties of the scaffolds and did not hinder their bioactivity in simulated body fluid. In vitro biocompatibility assessment was carried out by qualitative evaluation of the morphology of osteoblast-like cells (MG-63) seeded onto the scaffolds. The cells were shown to attach and spread on both uncoated scaffolds and cellulose nanowhisker-coated scaffolds, thus cellulose nanowhisker coating seems to have no negative influence on the behavior of MG-63 cells. The obtained bioactive and biocompatible composite scaffolds represent promising candidates for bone tissue engineering applications.
Date Issued
2014-10-10
Date Acceptance
2014-10-10
Citation
RSC Advances, 2014, 4 (99), pp.56156-56164
ISSN
2046-2069
Publisher
Royal Society of Chemistry
Start Page
56156
End Page
56164
Journal / Book Title
RSC Advances
Volume
4
Issue
99
Copyright Statement
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
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Publication Status
Published
Date Publish Online
2014-10-10