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  5. The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014
 
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The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014
File(s)
93dd07d1-c8e6-4978-b645-aa6a0278f53d_12753_-_Emma_Slaymaker.pdf (1.72 MB)
Published version
OA Location
https://gatesopenresearch.org/articles/1-4/v1
Author(s)
Slaymaker, Emma
McLean, Estelle
Wringe, Alison
Calvert, Clara
Marston, Milly
more
Type
Journal Article
Abstract
Timely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards transmission of infection.  Reliable, population-based estimates of new infections are difficult to obtain for the generalised epidemics in sub-Saharan Africa.  Mortality data indicate disease burden and, if disaggregated along the continuum from diagnosis to treatment, can also reflect the coverage and quality of different HIV services.  Neither routine statistics nor observational clinical studies can estimate mortality prior to linkage to care nor following disengagement from care.  For this, population-based data are required. The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa brings together studies in Kenya, Malawi, South Africa, Tanzania, Uganda, and Zimbabwe.  Eight studies have the necessary data to estimate mortality by HIV status, and seven can estimate mortality at different stages of the HIV care continuum.  This data note describes a harmonised dataset containing anonymised individual-level information on survival by HIV status for adults aged 15 and above. Among PLHIV, the dataset provides information on survival during different periods: prior to diagnosis of infection; following diagnosis but before linkage to care; in pre-antiretroviral treatment (ART) care; in the first six months after ART initiation; among people continuously on ART for 6+ months; and among people who have ever interrupted ART.
Date Issued
2017-11-06
Date Acceptance
2017-11-01
Citation
Gates Open Research, 2017, 1, pp.4-4
URI
http://hdl.handle.net/10044/1/58899
DOI
https://www.dx.doi.org/10.12688/gatesopenres.12753.1
ISSN
2572-4754
Publisher
F1000Research
Start Page
4
End Page
4
Journal / Book Title
Gates Open Research
Volume
1
Copyright Statement
© 2017 Slaymaker E et al. This is an open access article distributed under the terms of the Creative Commons Attribution Licence which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (https://creativecommons.org/licenses/by/4.0/)
Sponsor
Medical Research Council (MRC)
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/29528045
Grant Number
MR/K010174/1B
Subjects
Anti-retroviral therapy
HIV
HIV care continuum
HIV incidence
Longitudinal
Mortality
Population based
Sub-Saharan Africa
Publication Status
Published
Coverage Spatial
United States
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