Challenges and opportunities in controlling mosquito-borne infections
File(s)
Accepted version
Author(s)
Ferguson, Neil M
Type
Journal Article
Abstract
Mosquito-borne diseases remain a major cause of morbidity and mortality across the tropical regions. Despite much progress in the control of malaria, malaria-associated morbidity remains high, whereas arboviruses—most notably dengue—are responsible for a rising burden of disease, even in middle-income countries that have almost completely eliminated malaria. Here I discuss how new interventions offer the promise of considerable future reductions in disease burden. However, I emphasize that intervention programmes need to be underpinned by rigorous trials and quantitative epidemiological analyses. Such analyses suggest that the long-term goal of elimination is more feasible for dengue than for malaria, even if malaria elimination would offer greater overall health benefit to the public.
Date Issued
2018-07-26
Date Acceptance
2018-05-24
Citation
Nature, 2018, 559 (7715), pp.490-497
ISSN
0028-0836
Publisher
Nature Publishing Group
Start Page
490
End Page
497
Journal / Book Title
Nature
Volume
559
Issue
7715
Copyright Statement
© The Author(s).
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000439850800038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
PLASMODIUM-FALCIPARUM MALARIA
ANTIBODY-DEPENDENT ENHANCEMENT
AEDES-AEGYPTI
DENGUE VIRUS
ANOPHELES-STEPHENSI
GLOBAL DISTRIBUTION
CONTROLLED-TRIAL
VECTOR CONTROL
LATIN-AMERICA
GENE DRIVE
Publication Status
Published
Date Publish Online
2018-07-25