His bundle pacing, learning curve, procedure characteristics, safety, and feasibility: Insights from a large international observational study
File(s)HisBundlePacingLearningCurve.pdf (735.6 KB)
Published version
Author(s)
Type
Journal Article
Abstract
Background
His‐bundle pacing (HBP) provides physiological ventricular activation. Observational studies have demonstrated the techniques feasibility however, data has come from a limited number of centres.
Objectives
We set out to explore contemporary global practise in HBP focusing on learning curve, procedural characteristics and outcomes.
Methods
This is a retrospective, multi‐centre observational study of patients undergoing attempted HBP at seven centres. Pacing indication, fluoroscopy time, HBP thresholds and lead re‐intervention and deactivation rates were recorded. Where centres had systematically recorded implant success rates from the outset, these were collated.
Results
529 patients underwent attempted HBP during the study period (2014‐19) with mean follow‐up of 217±303 days. Most implants were for bradycardia indications.
In the three centres with systematic collation of all attempts, overall implant success rate was 81% which improved to 87% after completion of 40 cases.
All seven centres reported data on successful implants. Mean fluoroscopy time was 11.7±12.0 minutes, His‐bundle capture threshold at implant was 1.4±0.9V at 0.8±0.3 ms and was 1.3±1.2V at 0.9±0.2ms at last device check.
HBP lead re‐intervention or deactivation (for lead displacement or rise in threshold) occurred in 7.5% of successful implants.
There was evidence of a learning curve: fluoroscopy time and HBP capture threshold reduced with greater experience, plateauing after ~30‐50 cases.
Conclusion
We found that it is feasible to establish a successful HBP program, using the currently available implantation tools. For physicians who are experienced at pacemaker implantation the steepest part of the learning curve appears to be over the first 30‐50 cases.
His‐bundle pacing (HBP) provides physiological ventricular activation. Observational studies have demonstrated the techniques feasibility however, data has come from a limited number of centres.
Objectives
We set out to explore contemporary global practise in HBP focusing on learning curve, procedural characteristics and outcomes.
Methods
This is a retrospective, multi‐centre observational study of patients undergoing attempted HBP at seven centres. Pacing indication, fluoroscopy time, HBP thresholds and lead re‐intervention and deactivation rates were recorded. Where centres had systematically recorded implant success rates from the outset, these were collated.
Results
529 patients underwent attempted HBP during the study period (2014‐19) with mean follow‐up of 217±303 days. Most implants were for bradycardia indications.
In the three centres with systematic collation of all attempts, overall implant success rate was 81% which improved to 87% after completion of 40 cases.
All seven centres reported data on successful implants. Mean fluoroscopy time was 11.7±12.0 minutes, His‐bundle capture threshold at implant was 1.4±0.9V at 0.8±0.3 ms and was 1.3±1.2V at 0.9±0.2ms at last device check.
HBP lead re‐intervention or deactivation (for lead displacement or rise in threshold) occurred in 7.5% of successful implants.
There was evidence of a learning curve: fluoroscopy time and HBP capture threshold reduced with greater experience, plateauing after ~30‐50 cases.
Conclusion
We found that it is feasible to establish a successful HBP program, using the currently available implantation tools. For physicians who are experienced at pacemaker implantation the steepest part of the learning curve appears to be over the first 30‐50 cases.
Date Issued
2019-10
Date Acceptance
2019-07-07
Citation
Journal of Cardiovascular Electrophysiology, 2019, 30 (10), pp.1984-1993
ISSN
1045-3873
Publisher
Wiley
Start Page
1984
End Page
1993
Journal / Book Title
Journal of Cardiovascular Electrophysiology
Volume
30
Issue
10
Copyright Statement
© 2019 The Authors. This is an open access article under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Sponsor
British Heart Foundation
British Heart Foundation
British Heart Foundation
Identifier
https://onlinelibrary.wiley.com/doi/abs/10.1111/jce.14064
Grant Number
FS/13/44/30291
CS/15/3/31405
FS/15/53/31615
Subjects
Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Cardiovascular System & Cardiology
His bundle pacing
His bundle pacing characteristics
His bundle pacing feasibility
His bundle pacing learning curve
physiological pacing
HEART-FAILURE
PERMANENT
His bundle pacing
His bundle pacing characteristics
His bundle pacing feasibility
His bundle pacing learning curve
physiological pacing
Cardiovascular System & Hematology
1102 Cardiorespiratory Medicine and Haematology
Publication Status
Published
Date Publish Online
2019-08-02