Copper(I)-Phosphinite Complexes in Click Cycloadditions: Three-Component Reactions and Preparation of 5-Iodotriazoles
File(s)
Accepted version
Published version
Author(s)
Diez-Gonzalez, S
Lal, S
Perez, J
Crosbie, P
Type
Journal Article
Abstract
The remarkable activity displayed by copper(I)-
phosphinite complexes of general formula [CuBr(L)] in two
challenging cycloadditions is reported: a) the one pot
azidonation/cycloaddition from boronic acids, NaN3 and terminal
alkynes; b) the cycloaddition of azides and iodoalkynes. These airstable
catalysts led to very good results in both cases and the
expected triazoles could be isolated pure under ‘Click-suitable’
conditions.
phosphinite complexes of general formula [CuBr(L)] in two
challenging cycloadditions is reported: a) the one pot
azidonation/cycloaddition from boronic acids, NaN3 and terminal
alkynes; b) the cycloaddition of azides and iodoalkynes. These airstable
catalysts led to very good results in both cases and the
expected triazoles could be isolated pure under ‘Click-suitable’
conditions.
Date Issued
2016-06-13
Date Acceptance
2016-04-04
Citation
ChemCatChem, 2016, 8 (13), pp.2222-2226
ISSN
1867-3880
Publisher
Wiley
Start Page
2222
End Page
2226
Journal / Book Title
ChemCatChem
Volume
8
Issue
13
Copyright Statement
© 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.This is an open access article under the terms of the Creative Commons At-tribution License, which permits use, distribution and reproduction in anymedium, provided the original work is properly cited.
License URL
Sponsor
Engineering & Physical Science Research Council (EPSRC)
The Royal Society
Grant Number
EP/K030760/1
RG2015 R1
Subjects
Organic Chemistry
Publication Status
Published