Relative ultraviolet sensitivity of selected antibiotic resistance genes in waterborne bacteria
File(s)
Accepted version
Author(s)
Destiani, R
Templeton, MR
Kowalski, W
Type
Journal Article
Abstract
This study investigated the ability of monochromatic ultraviolet (UV) light at 254 nm applied at typical drinking water disinfection doses to damage the antibiotic-resistant genes mph(A), sul1, tet-A, and bla-Tem1 in waterborne bacteria. UV sensitivity rank was bla-TEM1 > tet-A > sul1 > mph(A), which is consistent with predictions of a previously presented genomic-based UV sensitivity model. It is the first time that predictions of the relative UV sensitivity of antibiotic resistance genes have been validated with experimental data and suggest that such modeling is useful for determining the UV sensitivity of other genes in waterborne microorganisms.
Date Issued
2018-07-06
Date Acceptance
2017-10-30
Citation
Environmental Engineering Science, 2018, 35 (7), pp.770-774
ISSN
1092-8758
Publisher
Mary Ann Liebert
Start Page
770
End Page
774
Journal / Book Title
Environmental Engineering Science
Volume
35
Issue
7
Copyright Statement
© Mary Ann Liebert, Inc. Final publication is available from Mary Ann Liebert, Inc., publishers https://www.liebertpub.com/doi/10.1089/ees.2017.0179
Subjects
Science & Technology
Technology
Life Sciences & Biomedicine
Engineering, Environmental
Environmental Sciences
Engineering
Environmental Sciences & Ecology
antibiotic resistance genes
disinfection
genomic modeling
UV disinfection
waterborne pathogens
WASTE-WATER
DRINKING-WATER
DNA
DISINFECTION
DAMAGE
0502 Environmental Science And Management
0907 Environmental Engineering
Environmental Engineering
Publication Status
Published online