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  4. Detecting knee osteoarthritis and its discriminating parameters using random forests
 
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Detecting knee osteoarthritis and its discriminating parameters using random forests
File(s)
1-s2.0-S1350453317300413-main.pdf (2.23 MB)
Published version
Author(s)
Kotti, M
Duffell, LD
Faisal, AA
McGregor, AH
Type
Journal Article
Abstract
T
his
paper
tackles the problem of automatic detection of knee osteoarthritis.
A computer system is
built that takes as input the body kinetics and produces as output
not only
an estimation of presence
of the knee osteoarthritis
,
as previous
ly
do
ne in
the literature
, but also
the most discriminating
parameters along with
a set of rules on how this decision was reached.
This
fills the gap of
interpretability between the medical and the
engineering
approaches
.
W
e collected locomotion data
from 47 su
bjects with knee osteoart
hritis and 47 healthy subjects.
Osteoarthritis subjects were
recruited from hospital clinics and GP surgeries, and age and sex matched heathy subjects from the
local community
.
S
ubjects walked on a walkway
equipped
with two force p
lates with
piezoelectric 3
-
component force sensors
.
Parameters of the vertical, anterior
-
pos
terior, and medio
-
lateral ground
reaction forces,
such as
mean value, push
-
off time, and slope
,
were extracted.
Then r
andom forest
regressors
map those
parameters
v
ia rule induction
to
the degree of kne
e osteoarthritis.
To boost
generalisation ability
,
a subject
-
independent protocol is employed.
The 5
-
fold cross
-
validated
accuracy is 72.61%±
4.2
4%.
W
e show that with 3 steps or less
a reliable clinical measure can be
extracted
in a rule
-
based approach
when the dataset is analysed appropriately.
Date Issued
2017-02-24
Date Acceptance
2017-02-05
Citation
Medical Engineering and Physics, 2017, 43, pp.19-29
URI
http://hdl.handle.net/10044/1/44353
DOI
https://www.dx.doi.org/10.1016/j.medengphy.2017.02.004
ISSN
1350-4533
Publisher
Elsevier
Start Page
19
End Page
29
Journal / Book Title
Medical Engineering and Physics
Volume
43
Copyright Statement
© 2017 The Authors. Published by Elsevier Ltd on behalf of IPEM.
This is an open access article under the CC BY license. (http://creativecommons.org/licenses/by/4.0/)
Sponsor
Engineering & Physical Science Research Council (EPSRC)
Grant Number
N/A
Subjects
Science & Technology
Technology
Engineering, Biomedical
Engineering
Knee osteoarthritis
Machine learning
Random forests
Ground reaction forces
GROUND REACTION FORCE
PRINCIPAL COMPONENT ANALYSIS
TOE-OUT
GAIT
WALKING
SEVERITY
CLASSIFICATION
ACTIVATION
STRATEGIES
MOVEMENT
Biomedical Engineering
02 Physical Sciences
09 Engineering
11 Medical And Health Sciences
Publication Status
Published
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