Neonatal sepsis and antimicrobial resistance in Africa
File(s)
Accepted version
Author(s)
Type
Journal Article
Abstract
Mortality rates in children younger than 5 years have reduced by half globally since 1990, but neonatal mortality rates remain high and far from the Sustainable Development Goal target of less than 12 deaths per 1000 livebirths by 2030.1
Sepsis is a leading cause of death in the first 28 days of life, particularly in sub-Saharan Africa. Bacterial sepsis is dominated by Gram-negative pathogens with substantial antimicrobial resistance, contributing to this region having the highest death rates attributable to antimicrobial resistance globally.2
WHO's antibiotic treatment guidelines have not kept pace with the exponential rise of antimicrobial resistance in sub-Saharan Africa, potentially exacerbating neonatal sepsis deaths. We, as representatives of the African Neonatal Association, call for urgent action and innovation (panel).
Sepsis is a leading cause of death in the first 28 days of life, particularly in sub-Saharan Africa. Bacterial sepsis is dominated by Gram-negative pathogens with substantial antimicrobial resistance, contributing to this region having the highest death rates attributable to antimicrobial resistance globally.2
WHO's antibiotic treatment guidelines have not kept pace with the exponential rise of antimicrobial resistance in sub-Saharan Africa, potentially exacerbating neonatal sepsis deaths. We, as representatives of the African Neonatal Association, call for urgent action and innovation (panel).
Date Issued
2023-10-01
Date Acceptance
2023-06-23
Citation
The Lancet Child & Adolescent Health, 2023, 7 (10), pp.677-679
ISSN
2352-4642
Publisher
Elsevier
Start Page
677
End Page
679
Journal / Book Title
The Lancet Child & Adolescent Health
Volume
7
Issue
10
Copyright Statement
© 2023 Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/37604175
PII: S2352-4642(23)00167-0
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2023-08-18