An international, prospective cohort study comparing non-absorbable versus absorbable sutures for skin surgery: the CANVAS service evaluation
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Accepted version
Author(s)
Type
Journal Article
Abstract
Background
Absorbable or non-absorbable sutures can be used for superficial skin closure following excisional skin surgery. There is no consensus among clinicians nor high-quality evidence supporting the choice of suture. The aim of the present study was to determine current suture use and complications at 30 days after excisional skin surgery.
Methods
An international, prospective service evaluation of adults undergoing excision of skin lesions (benign and malignant) in primary and secondary care was conducted from 1 September 2020 to 15 April 2021. Routine patient data collected by UK and Australasian collaborator networks were uploaded to REDCap©. Choice of suture and risk of complications were modelled using multivariable logistic regression.
Results
Some 3494 patients (4066 excisions) were included; 3246 (92.9 per cent) were from the UK and Ireland. Most patients were men (1945, 55.7 per cent), Caucasian (2849, 81.5 per cent) and aged 75–84 years (965, 27.6 per cent). The most common clinical diagnosis was basal cell carcinoma (1712, 42.1 per cent). Dermatologists performed most procedures, with 1803 excisions (44.3 per cent) on 1657 patients (47.4 per cent). Most defects were closed primarily (2856, 81.9 per cent), and there was equipoise in regard to use of absorbable (2127, 57.7 per cent) or non-absorbable (1558, 42.2 per cent) sutures for superficial closure. The most common complications were surgical-site infection (103, 2.9 per cent) and delayed wound healing (77, 2.2 per cent). In multivariable analysis, use of absorbable suture type was associated with increased patient age, geographical location (UK and Ireland), and surgeon specialty (oral and maxillofacial surgery and plastic surgery), but not with complications.
Conclusion
There was equipoise in suture use, and no association between suture type and complications. Definitive evidence from randomized trials is needed.
Absorbable or non-absorbable sutures can be used for superficial skin closure following excisional skin surgery. There is no consensus among clinicians nor high-quality evidence supporting the choice of suture. The aim of the present study was to determine current suture use and complications at 30 days after excisional skin surgery.
Methods
An international, prospective service evaluation of adults undergoing excision of skin lesions (benign and malignant) in primary and secondary care was conducted from 1 September 2020 to 15 April 2021. Routine patient data collected by UK and Australasian collaborator networks were uploaded to REDCap©. Choice of suture and risk of complications were modelled using multivariable logistic regression.
Results
Some 3494 patients (4066 excisions) were included; 3246 (92.9 per cent) were from the UK and Ireland. Most patients were men (1945, 55.7 per cent), Caucasian (2849, 81.5 per cent) and aged 75–84 years (965, 27.6 per cent). The most common clinical diagnosis was basal cell carcinoma (1712, 42.1 per cent). Dermatologists performed most procedures, with 1803 excisions (44.3 per cent) on 1657 patients (47.4 per cent). Most defects were closed primarily (2856, 81.9 per cent), and there was equipoise in regard to use of absorbable (2127, 57.7 per cent) or non-absorbable (1558, 42.2 per cent) sutures for superficial closure. The most common complications were surgical-site infection (103, 2.9 per cent) and delayed wound healing (77, 2.2 per cent). In multivariable analysis, use of absorbable suture type was associated with increased patient age, geographical location (UK and Ireland), and surgeon specialty (oral and maxillofacial surgery and plastic surgery), but not with complications.
Conclusion
There was equipoise in suture use, and no association between suture type and complications. Definitive evidence from randomized trials is needed.
Date Issued
2023-02-08
Date Acceptance
2023-01-31
Citation
British Journal of Surgery, 2023, pp.1-9
ISSN
0007-1323
Publisher
Oxford University Press
Start Page
1
End Page
9
Journal / Book Title
British Journal of Surgery
Copyright Statement
© The Author(s) 2023. Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Copyright © 2023 Oxford University Press. This is a pre-copy-editing, author-produced version of an article accepted for publication in BJS following peer review. The definitive publisher-authenticated version Alice Lee, Guy H M Stanley, Ryckie G Wade, Daniele Berwick, Victoria Vinicombe, Brogan K Salence, Esra Musbahi, Anderson R C S De Poli, Mihaela Savu, Jonathan M Batchelor, Rachel A Abbott, Matthew D Gardiner, Aaron Wernham, David Veitch, the CANVAS collaborative, International, prospective cohort study comparing non-absorbable versus absorbable sutures for skin surgery: CANVAS service evaluation, British Journal of Surgery, 2023;, znad008, is available online at: https://doi.org/10.1093/bjs/znad008
Copyright © 2023 Oxford University Press. This is a pre-copy-editing, author-produced version of an article accepted for publication in BJS following peer review. The definitive publisher-authenticated version Alice Lee, Guy H M Stanley, Ryckie G Wade, Daniele Berwick, Victoria Vinicombe, Brogan K Salence, Esra Musbahi, Anderson R C S De Poli, Mihaela Savu, Jonathan M Batchelor, Rachel A Abbott, Matthew D Gardiner, Aaron Wernham, David Veitch, the CANVAS collaborative, International, prospective cohort study comparing non-absorbable versus absorbable sutures for skin surgery: CANVAS service evaluation, British Journal of Surgery, 2023;, znad008, is available online at: https://doi.org/10.1093/bjs/znad008
Identifier
https://academic.oup.com/bjs/article-lookup/doi/10.1093/bjs/znad008
Publication Status
Published online
Article Number
znad008
Date Publish Online
2023-02-08