Decoding time-varying functional connectivity networks via linear graph embedding methods
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Published version
Author(s)
Type
Journal Article
Abstract
An exciting avenue of neuroscientific research involves quantifying the time-varying prop-
erties of functional connectivity networks. As a result, many methods have been proposed to
estimate the dynamic properties of such networks. However, one of the challenges associated
with such methods involves the interpretation and visualization of high-dimensional, dynamic
networks. In this work, we employ graph embedding algorithms to provide low-dimensional
vector representations of networks, thus facilitating traditional objectives such as visualization,
interpretation and classification. We focus on linear graph embedding methods based on prin-
cipal component analysis and regularized linear discriminant analysis. The proposed graph
embedding methods are validated through a series of simulations and applied to fMRI data
from the Human Connectome Project.
erties of functional connectivity networks. As a result, many methods have been proposed to
estimate the dynamic properties of such networks. However, one of the challenges associated
with such methods involves the interpretation and visualization of high-dimensional, dynamic
networks. In this work, we employ graph embedding algorithms to provide low-dimensional
vector representations of networks, thus facilitating traditional objectives such as visualization,
interpretation and classification. We focus on linear graph embedding methods based on prin-
cipal component analysis and regularized linear discriminant analysis. The proposed graph
embedding methods are validated through a series of simulations and applied to fMRI data
from the Human Connectome Project.
Date Issued
2017-03-20
Date Acceptance
2017-02-27
Citation
Frontiers in Computational Neuroscience, 2017, 11
ISSN
1662-5188
Publisher
Frontiers Media
Journal / Book Title
Frontiers in Computational Neuroscience
Volume
11
Copyright Statement
© 2017 Monti, Lorenz, Hellyer, Leech, Anagnostopoulos and Montana. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Subjects
Science & Technology
Life Sciences & Biomedicine
Mathematical & Computational Biology
Neurosciences
Neurosciences & Neurology
dynamic networks
graph embedding
functional connectivity
brain decoding
visualization
COMPLEX BRAIN NETWORKS
WORKING-MEMORY
FMRI
REDUCTION
FRAMEWORK
REGIONS
SYSTEMS
CORTEX
SERIES
ROLES
1103 Clinical Sciences
1109 Neurosciences
Publication Status
Published
Article Number
14