Zinc Cream and Reliability of Tuberculosis Skin Testing
File(s)
Author(s)
Type
Journal Article
Abstract
In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sites caused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc defi ciency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune responses enough to improve diagnosis.
Date Issued
2007-07-31
Date Acceptance
2007-07-01
Citation
Emerging Infectious Diseases, 2007, 13 (7), pp.1101-1104
ISSN
1080-6059
Publisher
Centers for Disease Control and Prevention
Start Page
1101
End Page
1104
Journal / Book Title
Emerging Infectious Diseases
Volume
13
Issue
7
Copyright Statement
All materials published in Emerging Infectious Diseases are in the public domain and can be used without permission. Rao VB, Pelly TF, Gilman RH, Cabrera L, Delgado J, Soto G, et al. Zinc cream and reliability of tuberculosis skin testing. Emerg Infect Dis [serial on the Internet]. 2007 Jul [date cited]. Available from http://wwwnc.cdc.gov/eid/article/13/7/07-0227
Subjects
Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
IMMUNOLOGY
INFECTIOUS DISEASES
MALNUTRITION
Administration, Topical
Adult
Diagnosis, Differential
Double-Blind Method
False Negative Reactions
Female
Humans
Male
Nutritional Status
Peru
Reproducibility of Results
Risk Factors
Sensitivity and Specificity
Skin
Social Class
Socioeconomic Factors
Trace Elements
Tuberculin Test
Tuberculosis
Zinc
Microbiology
1108 Medical Microbiology
1117 Public Health And Health Services
1103 Clinical Sciences
Publication Status
Published