Systemic manifestations of chronic obstructive pulmonary disease
File(s)
Accepted version
Author(s)
Warwick, E
Scourfield, A
Quint, J
Type
Journal Article
Abstract
Chronic obstructive pulmonary disease is one of the most common respiratory diseases worldwide, with a European prevalence of between 2 and 10%. It is characterized by progressive and non-reversible airflow obstruction. The Global Initiative for Chronic Lung Disease (2011) defines chronic obstructive pulmonary disease as: 'a common, preventable and treatable disease characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and co-morbidities contribute to the overall severity in individual patients'. Chronic obstructive pulmonary disease is not only thought to be associated with airway inflammation but also systemic inflammation (Aryal et al, 2013) and it is this systemic inflammation which is thought to be responsible for some of the systemic manifestations and comorbidities of the disease.
Date Issued
2015-06-08
Date Acceptance
2015-06-08
Citation
British Journal of Hospital Medicine, 2015, 76 (6), pp.324-329
ISSN
1750-8460
Publisher
Mark Allen Healthcare
Start Page
324
End Page
329
Journal / Book Title
British Journal of Hospital Medicine
Volume
76
Issue
6
Copyright Statement
© 2015 The Authors
Publication Status
Published