Managing the burden of sickle-cell disease in Africa

File(s)

Piel et al - The Lancet Haematology - Managing the burden of sickle cell disease in Africa.pdf (81.7 KB)

Accepted version

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Author(s)

Piel, FB

Rees, DC

Williams, TN

Type

Journal Article

Abstract

Sickle-cell disease is a genetic disorder of growing public health importance worldwide.1 More than 300 000 homozygous neonates with sickle-cell anaemia (HbSS)—the most common form of sickle-cell disease worldwide1—are born every year, with three-quarters born in sub-Saharan Africa.2 Estimates based on demographic projections suggest that this number could increase to 400 000 by 2050.3 Little is known about the natural history of sickle-cell anaemia, especially in Africa, or the epidemiology of other clinically relevant forms of sickle-cell disease, such as HbSC disease and HbS-β-thalassaemia.

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Date Issued

2014-10-05

Date Acceptance

2014-10-05

Citation

The Lancet. Haematology, 2014, 1 (1), pp.e11-e12

URI

http://hdl.handle.net/10044/1/27130

DOI

https://www.dx.doi.org/10.1016/S2352-3026(14)70017-1

ISSN

2352-3026

Publisher

Elsevier

Start Page

e11

End Page

e12

Journal / Book Title

The Lancet. Haematology

Volume

1

Issue

1

Copyright Statement

© 2014, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Publication Status

Published