Identification of feasible regions using R-functions
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Published version
Author(s)
Kucherenko, S
Shah, N
Klymenko, OV
Type
Journal Article
Abstract
The primary objective of feasibility analysis is to identify and define the feasibility region, which represents the range of operational conditions (e.g., variations in process parameters) that ensure safe, reliable, and feasible process performance. This work introduces a novel feasibility analysis method that requires only that model constraints (e.g., defining product Critical Quality Attributes or process Key Performance Indicators) be explicitly provided or approximated by a closed-form function, such as a multivariate polynomial model. The method is based on V.L. Rvachev's R-functions, enabling an explicit analytical representation of the feasibility region without relying on complex optimization-based approaches. R-functions offer a framework for describing intricate geometric shapes and performing operations on them using implicit functions and inequality constraints. The theory of R-functions facilitates the identification of feasibility regions through algebraic manipulation, making it a more practical alternative to traditional optimization-based methods. The effectiveness of the proposed approach is demonstrated using a suite of well-known test cases from the literature.
Date Issued
2025-10-01
Date Acceptance
2025-08-25
Citation
Journal of Process Control, 2025, 154
ISSN
0959-1524
Publisher
Elsevier
Journal / Book Title
Journal of Process Control
Volume
154
Copyright Statement
© 2025 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
License URL
Subjects
Automation & Control Systems
CHEMICAL-PROCESS DESIGN
Design space
Engineering
Engineering, Chemical
FEASIBILITY
Feasibility analysis
INDEX
OPERATIONAL FLEXIBILITY
Pharmaceutical manufacturing
R -functions
Science & Technology
Technology
Publication Status
Published
Article Number
103539
Date Publish Online
2025-09-03